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My field of natural products pharmacology was founded by indigenous cultures who recognized that plants and fungi contain compounds that produce altered states of consciousness, leading to their buy jwh018 liquid for sale common use in religious ceremonies. While we may most often associate these naturally-occurring drugs with hallucinogens, the arguably most common natural product in use today is marijuana or Cannabis sativa.
Indigenous to India and China, Cannabis has been the subject of increasing decriminalization worldwide due in part to its clinical, medicinal effects in multiple sclerosis, cancer, and AIDS. In fact, the St. I became intrigued as to why buy jwh018 liquid for sale would go through the trouble of making a synthetic marijuana when the real thing is so readily cultivated worldwide, albeit illegally in most locales.
So what is it? The compound most commonly found in these products is a chemical first synthesized by the well-known Clemson University organic chemist, Prof John W Huffman: Another compound, found in Spice products sold in Germany, is an analog of CP, a cannabinoid developed by Pfizer over 20 years ago. Known as 1-pentyl 1-naphthoyl indoleor the more proper IUPAC name of Naphthalenyl- 1-pentylindolyl methanone, JWH is one of buy jwh018 liquid for sale indoles, pyrroles, and indenes synthesized by the Huffman laboratory to develop cannabimimetics, drugs that mimic the effect of cannabinoids such as THC.
The primary goal of these buy jwh018 liquid for sale was to create pharmacological probes to 1 determine the structure-activity relationships of these compounds and 2 tease out the physiological function of subtypes of receptors we have for cannabinoids: What does it do? Much of the biological assessment work of Dr. Martin of the Medical College of Virginia. Martin, a native of North Carolina, was a giant in the field and sadly left us two summers ago at the all-too-young age of 65 obituary. What does this mean?
Well, the CB1 receptor is the primary means by which cannabinoids exert their psychotropic effects. The CB2 receptor, on the other hand, appears to be more involved in pain and inflammation and is therefore a very active area of research for new therapeutics. Ward Frantz might be a bit hysterical at this point but I could be wrong. Human toxicology studies have not been done and the indole moiety of the drug dose raise the possibility that it may cause serotonin syndrome, a potentially fatal but relatively rare disorder.
Probably the reason it has now caught on. JWH is however already classified as illegal in several European and Scandinavian countries. Influence of the N-1 alkyl buy jwh018 liquid for sale length of cannabimimetic indoles upon CB 1 and CB 2 receptor binding. One thing that definitely can be problematic, especially compared to cannabis, is dosage; an average dose of JWH is only 2 or 3mg, and exceeding that can get uncomfortable in a hurry. I suspect that most people would be able to tell the difference in a double-blind study, and most would probably prefer cannabis.
Spice was made illegal here on the 23rd December but to be honest it has received very little interest and, as far as I am aware, very little uptake both pre- and post- legislation. A drug that has absolutely exploded in use over here in the last couple of months is Mephedrone 4MMC which is currently legal but buy jwh018 liquid for sale had a huge impact on UK society. Is this drug appearing over in the US and other buy jwh018 liquid for sale I am just amazed at how quickly it has become a huge craze over here.
Seems like most RCs are pretty much unknown in most areas. As for cost, that may be true of Spice, but pure JWH is much cheaper than cannabis per dose. Until employers and governments have widespread urine testing for this it will continue to be popular weather legal or not. Governments banning it raise awareness of it and also legitimize it as a substance that works at getting someone high.
Parsley, sage, rosemary or thyme? The potential carcinogenicity of the JWH compounds centers around that naphthalene ring hanging off the side. The studies with JWH showed that it was being metabolized via epoxidation in vitro, a pathway known to produce carcinogenic metabolites from many polycyclic aromatic hydrocarbons.
This group, however, is shared by nearly all of the JWH compounds, including the most commonly found ones, JWH and Thanks for the info, Ted. You might be interested in these anonymous toxicology reports: DRUGS… dangerous drugs that have killed millions of people! Alcohol and cigarettes are scientifically proven to be FAR more dangerous and poisonous to the human body then marajuana… but we all knew that already right?
Everyone has already known this for quite awhile and even taught their children this truth. Even before I became a bio-medical sciencetist, that was the general consensus of the public I was aware of.
Oh, btw, the only person with visible nipples in the Guardian article is me: I tend to try and persuade her that brisk walks and crossword puzzles are the best preventive. In my area, K2 popularity is spreading like wildfire. Many people are using it as an alternative to marijuana because K2 does not show up on drug tests, and everyone seems to be on probation nowadays.
It may turn out that the wide spread interest in this synthetic pushes lawmakers to realize the demand for the real stuff and the opportunities to legalize and tax it to help our current buy jwh018 liquid for sale problems. California may be voting on full legalization this year.
For real…what good comes from drinking? Have you ever heard of a Mothers Against High Drivers? So, buy jwh018 liquid for sale could sell it, but not be around it. I hate these mixed-up laws. I know i would be back in prison if it wasent for JWH, its better than nothing, or using illegal drugs buy jwh018 liquid for sale blowing a hot ua. So i say keep it legal, its suposadly a free country anyway right?
But thats a whole other subject. They will make k2 illegal. Nothing posted here will stop it, either. You can buy all the alcohol you want and get out on these roads and kill someone or yourself. How many guys you know smoke some weed or k2 and go home and beat up on their families. Now how many times have you heard of someone downing a bottle of something and doing just that? What else do they say?
Gateway to what, my refrigerator? Cigarettes have killed millions upon millions of people in this country alone, and yet you can smoke all buy jwh018 liquid for sale want. My stepfather has been a paramedic for over 25 years and he tells me the number of dead people he has had to scrape off the road due to alcohol is enormous, but never has he had to deal with that because someone smoked a little pot and ran a family down.
How buy jwh018 liquid for sale times have any of you smoked some pot, and woke up the next morning with someone you do not even know, and spent that whole day next to the toilet wishing you were dead, puking your brains out? How many times buy jwh018 liquid for sale alcohol been a major factor in someone cheating on a spouse?
Ill quit ranting buy jwh018 liquid for sale as I said it will do no good. The United States will never legalize marijuana and will eventually make any thing like it illegal.
I personally have used pep spice because i had a job interview coming up and i knew they were gonna piss test me so this was cool to use until after the test. Make sure you get ask for, and receive beforehand a CA Certificate of Analysis. This is the way it was done with most other synthetic psychotropics before they went scheduled sometimes after…. Interesting…I did a search on Google and found this website that sells a product like buy jwh018 liquid for sale, seems to be legal for now:.
Go check it out right NOW! Very nice article, will share with some people. Will be interesting to see what happens to K2 over the next year or so.
Yes I smoked the real thing, which I got in trouble for it. I was in buy jwh018 liquid for sale EF4 tornado on this very day in I was airlifted to the Springfield, Mo, At St. Anyway, after being at St. Well… my family dr put me on Methadone, since I had been on the duragesic patches after being released from the hospital.
To reduce the pain that was my only option. PTSD thanks to that twister. Like I said, I got in trouble for possession. For by what judgment you judge, you shall be judged.
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With jwh — you easily can take too much and get too high and really have a horrible time. See above… I blew it up so you can read it better. There have been a lot more states cracking down recently. I really enjoyed the availability of herbal incense as a legal alternative.
Everyone just wants to be left alone with their favorite JWH compound without having to break the law. As both a user of marijuana, as well as having much experience buy jwh018 liquid for sale experimenting with a few forms of the JWH compounds, I agree with a lot of what has been said by the board. Looking for the alternative substance is what powered my first search for the analogue.