Linkage - Part 1
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Some Recombination frequency practice problems Questions from undergraduate days. These are just meant as suggestions to guide you to the kinds of problems you should be able to cope with. Another suggested problem and review book: Schaum's Outline series, Theory and Problems of Genetics 3rd ed. A coin is flipped and comes up heads. What is the probability that the next flip will yield heads?
What about the third and fourth flips? A plant heterozygous for four independently assorting genes AaBbCcDd is self fertilized. Determine the expected frequency of the following genotypes in the progeny: Assuming incomplete dominance, how many different phenotypes will be present in the progeny?
How many chromatids and centromeres per cell will a diploid organisms with a haploid number of 26 have at the end of a metaphase I; b metaphase II; c telophase I; d telophase II and e mitosis? The following progeny and numbers of each are produced: AaBb ; aabb ; Aabb 36 recombination frequency practice problems aaBb Which progeny are recombinants and what is the recombination frequency between A and B?
If no crossing over occurs between the centromere and the gene, what is the arrangement of the spores in the ascus and is this a first or a second division segregation pattern? If a single cross over occurs between the recombination frequency practice problems and the centromere in Neurospora, why is the spore pattern called a second-division segregation pattern why does segregation not occur in the first division?
How is the frequency of tetratype asci compared to that of nonparental ditype asci? Consider three linked genes in corn: A testcross is made between a triple heterozygote and a homozygous recessive. The following progeny were observed:. Determine which classes are the most frequent non-recombinants. This will recombination frequency practice problems you what the heterozygote was.
Determine the order by comparing the DCO classes to the parental classes. Only one order will work here. The presence of 4 equally frequent recombination frequency practice problems classes and 4 equally frequent minority classes suggests that two genes are linked and one gene is not.
You expect a ratio of 1: From the data, some of the genes must be linked. If all three genes were linked, you would observe only 2 majority classes. Start with genes that have the largest distances recombination frequency practice problems them since they must be near the ends.